Table 1.
List of central genes (hub-bottleneck nodes) of the main connected component (only including query genes)
| Genes | Description | Degree | Centrality * |
|---|---|---|---|
| GNRHR | Gonadotropin-releasing hormone receptor | 22 | 0.05 |
| PRL | Prolactin precursor | 21 | 1.00 |
| ADRB2 | Beta-2 adrenergic receptor | 20 | 0.77 |
| LHB | Lutropin subunit beta | 18 | 0.04 |
| AMCF-II | Alveolar macrophage chemotactic factor 2 | 17 | 0.19 |
| CDH1 | Cadherin-1 | 14 | 0.02 |
| MMP-13 | Matrix Metalloproteinase-13 | 13 | o.57 |
| INSR | Insulin receptor | 12 | 0.00 |
| IGF2 | Insulin-like growth factor II | 11 | 0.13 |
*
Normalized betweenness centrality; Red color: up-regulation; Green color: down-regulation.