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Effect of NZX on growth kinetics of M. tuberculosis. (A) Time-kill assay. BCG treated once with 0.8, 1.6 or 3.2 μM NZX at day 0. Graph depict relative luminescence units (RLU) after sampling each condition twice per time point. (B) Graph depicts growth kinetics of M. tuberculosis H37Rv using the MGIT960-culture system for a period of 18 days. Bacteria were treated once with 3.2, 6.3 or 12.5 μM NZX at day 0. Data depicts an average of three replicates.
