Fig. 1. (a) Examples of protein nanostructures (PNs) in Nature: tripartite neurotoxin (PDB: 3BTA), tetrameric avidin (PDB: ; 1AVE), actin polymer and 3D virus capsids (PDB: ; 1CWP). (b) Schematic overview and design of distinct PNs formed by precise interactions of protein building blocks (PBs), supramolecular linkers (SLs) and supramolecular recognition motifs yielding e.g. dimeric, trimeric or ring-like nanostructures as examples. Protein images were created using the NGL viewer.240.