. Author manuscript; available in PMC: 2018 Dec 11.

Published in final edited form as: J Am Chem Soc. 2016 Oct 26;138(44):14658–14667. doi: 10.1021/jacs.6b07981

Table 3.

Tunable, Catalyst-Controlled Amination^*

graphic file with name nihms-995962-t0004.jpg

A: HfsNH₂ (0.25 mmol), 10 mol % of AgOTf, 12 mol % of ^tBu₃tpy,3.5 equiv of PhIO, CH₂Cl₂, 4 Å MS, 4 h, rt. I: DfsNH₂ (0.25 mmol), 10 mol % of AgOTf, 12 mol % of tpa, 1.2 equiv of PhIO, CH₂Cl₂, 4 Å MS, 1 h, rt.

Isolated yield.

NMR yield, Cl₃CCH₂Cl internal standard.

trans only, 6% rearranged.

3% rearranged.