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. 2018 Oct 29;128(1):75–84. doi: 10.1093/bmb/ldy035

Table 1.

Summary of antihypertensive treatment for pre-pregnancy hypertension

Variable Recommendation Controversy
Medications Methyldopa or labetalol Diuretics
Avoid ACE inhibitors
Blood-pressure goals Women with mild-moderate hypertension and a normal BMI may choose to discontinue the use or reduce the doses of antihypertensive agents. Specific blood-pressure levels for treatment and goal
Evaluation before pregnancy
  • Evaluate for secondary causesin presence of suggestivesymptoms or signs.

  • In women with a history ofhypertension for severalyears, evaluate for target-organdamage, includingleft ventricular hypertrophy, retinopathy.

Supplementations Calcium, antioxidants, low-dose aspirin (60 mg daily)
Lifestyle
  • Healthy body weight.

  • Adequate sodium and potassium intake.

The dose of sodium or potassium intake

ACE denotes angiotensin-converting enzyme, BMI body mass index.