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. 2018 Dec 4;13:8247–8268. doi: 10.2147/IJN.S179906

Table 2.

Release exponent (n), rate constant (k), and correlation coefficient (R2) for the two drug-loaded micelles

Samples Time interval (hours) pH=7.4 pH=5.0 pH=5.0+10 mM GSH
n k R2 n k R2 n k R2
mPEG-4sPLMBz 0–2 0.526 0.135 0.991 0.693 0.140 0.999
3–12 0.251 0.186 0.987 0.347 0.196 0.985
24–72 0.148 0.235 0.990 0.160 0.311 0.996
RGD-PEG-ss- 4sPLMBz 0–2 0.789 0.169 0.993 0.756 0.225 0.995 0.639 0.285 0.993
3–12 0.215 0.282 0.953 0.219 0.367 0.973 0.215 0.417 0.966
24–72 0.009 0.480 0.999 0.088 0.500 0.988 0.082 0.568 0.953

Abbreviations: GSH, glutathione; mPEG, methoxy poly(ethylene glycol); PEG, poly(ethylene glycol).