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. Author manuscript; available in PMC: 2019 Mar 26.
Published in final edited form as: Nature. 2018 Sep 26;562(7726):223–228. doi: 10.1038/s41586-018-0552-x

Extended data figure 10. Csf1r-iCre-targeted ECs contribute to adult organ vasculature.

Extended data figure 10

(a) 20 µm cryosections of 3 months old adult Csf1r-iCre;RosatdTom livers (n = 3) were immunolabelled for RFP and the EC marker VEGFR2 and the macrophage marker F4/80 or the liver EC sinusoidal EC marker MRC1 and then counterstained with DAPI; single channels are shown in grey scale. The white box indicates an area shown in higher magnification in Fig. 6h. Scale bars: 100 µm.

(b) Working model for the role of EMPs in generating extra-embryonic yolk sac and intra-embryonic organ ECs alongside their known role in generating myeloid and erythrocyte/megakaryocyte cells.