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. Author manuscript; available in PMC: 2018 Dec 11.
Published in final edited form as: Smart Health (Amst). 2018 Jul 7;9-10:88–100. doi: 10.1016/j.smhl.2018.07.007

Table 3.

Few of the groundings generated for the random walk TargetAgonist (d0, e1)_TargetAgonist (e1, d1)EnzymeSubstrated1, e2)(∧ _EnzymeInhibitor (e2, d2)

Tramadol,Mu-type opioid receptor,Morphine,Cytochrome P450 2C8,Pravastatin
Morphine,Mu-type opioid receptor,Tramadol,Cytochrome P450 3A4,Tadalafil
Hydromorphone,Mu-type opioid receptor,Morphine,Cytochrome P450 2D6,Amlodipine
Methadone,Mu-type opioid receptor,Oxycodone,Cytochrome P450 3A4,Risperidone
Oxycodone,Mu-type opioid receptor,Hydromorphone,Cytochrome P450 2D6,Risperidone