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Pharmacokinetic parameters of berberine and berberine8998 in SD rats.
| Drug | Dose (mg) | T max (h) | C max (ng/mL) | AUClast (h*ng/mL) | AUCinf (h*ng/mL) |
|---|---|---|---|---|---|
| Berberine | 70 | 1.5±1.0 | 55.1±49.3 | 312.4±165.2 | 397.6±170.4 |
| Berberine8998 | 70 | 3.0±1.7 | 230.3±70.2 | 2418.0±644.3 | 2519.0±653.5 |
