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. 2018 Feb 8;39(8):1393–1404. doi: 10.1038/aps.2017.144

Table 2.

The contribution and f m of CYPs to cryptotanshinone metabolism in HLMs.

CYP enzymes % Inhibition f m (%)
1A2 35.8 16.0
2A6 57.6 25.7
2C8 14.1 6.3
2C9 1.5 0.7
2C19 58.0 25.9
2D6 7.0 3.1
3A4 50.0 22.3