Table 2.
Examination of blood routine, blood biochemistry, coagulation index 6 weeks after the last hAECs transplantation in long-term toxicity test.
| Group | |||||
|---|---|---|---|---|---|
| Control | hAEC (low dose) | hAEC (high dose) | F value | P value | |
| TP | 63.58±5.00 | 61.39±5.00 | 62.10±4.00 | 0.526 | 0.597 |
| ALB | 44.76±7.00 | 42.15±6.00 | 42.26±5.00 | 0.305 | 0.740 |
| GLOB | 18.82±3.00 | 19.24±1.00 | 19.84±1.00 | 1.799 | 0.186 |
| ALT | 29.70±5.00 | 33.17±7.00 | 29.44±4.00 | 0.068 | 0.935 |
| AST | 121.60±2.00 | 114.48±2.00 | 119.14±2.00 | 0.199 | 0.821 |
| Tbil | 2.11±0.00 | 1.64±0.00 | 1.83±0.00 | 0.299 | 0.744 |
| ALP | 63.00±2.00 | 66.90±3.00 | 64.40±2.00 | 0.205 | 0.816 |
| Bun | 6.11±0.00 | 5.92±0.00 | 5.55±0.00 | 0.199 | 0.821 |
| CREA | 41.60±5.00 | 34.30±4.00 | 33.30±7.00 | 1.235 | 0.307 |
| GLU | 6.89±0.00 | 6.57±0.00 | 6.49±0.00 | 0.552 | 0.583 |
| K | 4.24±0.00 | 4.36±0.00 | 4.47±0.00 | 0.332 | 0.721 |
| Na | 142.50±2.00 | 143.60±1.00 | 143.50±2.00 | 0.515 | 0.604 |
| Cl | 99.39±2.00 | 102.32±1.00 | 101.27±2.00* | 3.865 | 0.034 |
| TG | 0.99±0.00 | 0.75±0.00 | 0.83±0.00 | 0.735 | 0.489 |
| TCHOL | 2.03±0.00 | 1.76±0.00 | 1.69±0.00 | 1.954 | 0.162 |
| CK | 841.00±4.00 | 719.80±4.00 | 722.00±2.00 | 0.538 | 0.590 |
| WBC | 4.57±2.00 | 3.00±1.00 | 3.59±0.00 | 1.875 | 0.174 |
| RBC | 7.53±0.00 | 7.72±0.00 | 7.72±0.00 | 0.307 | 0.738 |
| HGB | 13.49±0.00 | 13.96±0.00 | 12.49±3.00 | 0.243 | 0.786 |
| HCT | 39.64±2.00 | 41.12±1.00 | 40.64±0.00 | 0.290 | 0.751 |
| PLT | 967.60±1.00 | 922.50±1.00 | 1021.50±1.00 | 1.302 | 0.289 |
| MCV | 52.80±3.00 | 53.37±1.00 | 52.30±3.00 | 0.795 | 0.462 |
| MCH | 17.95±0.00 | 18.11±0.00 | 17.73±0.00 | 0.231 | 0.795 |
| MCHC | 34.02±0.00 | 33.95±0.00 | 33.58±0.00 | 0.378 | 0.689 |
| NEUT% | 11.78±4.00 | 17.99±6.00 | 11.72±5.00* | 3.759 | 0.037 |
| LYMPH% | 84.40±5.00 | 77.19±6.00 | 82.75±5.00** | 4.988 | 0.015 |
| MONO% | 2.69±0.00 | 3.36±1.00 | 3.18±0.00* | 3.389 | 0.049 |
| EO% | 1.13±0.00 | 1.46±0.00 | 1.34±0.00 | 1.182 | 0.323 |
| BASO% | 0.00±0.00 | 0.00±0.00 | 0.00±0.00 | 0.581 | 0.566 |
| RET# | 248.44±5.00 | 227.56±5.00 | 220.10±3.00 | 0.052 | 0.949 |
| APTT | 10.50±1.00 | 12.22±3.00 | 10.92±2.00 | 0.448 | 0.644 |
| Fbg-% | 0.19±0.00 | 0.18±0.00 | 0.18±0.00 | 0.064 | 0.939 |
| Fbg-T | 10.35±1.00 | 10.51±1.00 | 10.23±1.00 | 0.202 | 0.819 |
| PT | 9.99±0.00 | 10.42±0.00 | 10.24±0.00 | 0.025 | 0.975 |
| TT | 48.16±6.00 | 41.77±7.00 | 45.41±5.00 | 0.890 | 0.422 |