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Intracellular distributions of DOX, TPP−DOX and HA-ionic-TPP-DOX in MCF-7/ADR cells. Cells were exposed to DOX, TPP−DOX or HA-ionic-TPP-DOX solution at 37 °C for 1 h (A) and 4 h (B), and the mitochondria were stained with Mito-tracker Green FM, while the nuclei were stained with Hoechst 33342. The overlay between the fluorescence of TPP-DOX (red) and Mito-tracker (green) appears as yellow.
