Table 1.
Patient demographics and characteristics at baseline.
| DCM | ICM | HCM | Overall cohort | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Median | Min | Max | Median | Min | Max | Median | Min | Max | Median | Min | Max | P-value | |
| sST2 | 4288.5 | 2294.0 | 7172.8 | 3746.8 | 1735.1 | 6530.2 | 3843.0 | 3019.5 | 13207.4 | 4126.8 | 1735.1 | 13207.4 | .817 |
| H-FABP | 2.7 | 1.3 | 387.0 | 1.8 | 0.0 | 3.1 | 2.1 | 1.4 | 7.4 | 2.1 | 0.0 | 387.0 | .090 |
| GDF-15 | 732.4 | 594.3 | 118257.0 | 884.0 | 338.3 | 2074.6 | 711.1 | 695.3 | 1887.1 | 768.5 | 338.3 | 118257.0 | .965 |
| suPAR | 2275.2 | 1505.0 | 3294.5 | 2069.6 | 1053.2 | 3647.9 | 1671.2 | 1422.7 | 3137.1 | 2136.6 | 1053.2 | 3647.9 | .373 |
| Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | ||||||
| Heart rate (bpm) | 79.9 | 2.3 | 78.9 | 1.5 | 81.3 | 1.8 | 79.7 | 1.1 | .725 | ||||
| Blood pressure (systolic) | 123.0 | 5.0 | 150.7 | 6.3 | 130.7 | 7.7 | 137.4 | 4.3 | .007 | ||||
| Blood pressure (diastolic) | 82.0 | 3.6 | 87.4 | 2.8 | 89.8 | 4.6 | 86.0 | 2.0 | .333 | ||||
| QRS length (ms) | 118.9 | 8.0 | 119.6 | 9.1 | 131.6 | 17.2 | 121.9 | 5.8 | .698 | ||||
| EF (%) | 32.5 | 3.0 | 34.2 | 2.2 | 30.0 | 4.8 | 32.8 | 1.7 | .673 | ||||
| LVEDD (mm) | 60.8 | 2.4 | 61.6 | 3.4 | 62.0 | 3.8 | 61.4 | 1.9 | .974 | ||||
| LVESD (mm) | 49.2 | 3.3 | 50.1 | 3.8 | 54.2 | 5.8 | 50.6 | 2.3 | .730 | ||||
| LVESV (mL) | 102.9 | 16.0 | 102.4 | 9.9 | 133.7 | 20.6 | 109.5 | 8.3 | .310 | ||||
| Pulmonary arterial pressure (PAP) | 14.9 | 4.7 | 14.8 | 6.9 | 22.4 | 7.5 | 16.5 | 3.7 | .716 | ||||
| BNP (pg/mL) | 320.1 | 149.9 | 217.5 | 85.5 | 578.3 | 330.3 | 320.4 | 88.8 | .353 | ||||
| IL-6 (pg/mL) | 7.1 | 2.3 | 5.2 | 1.1 | 12.2 | 5.0 | 7.2 | 1.4 | .174 | ||||
| hsCRP (mg/L) | 6.0 | 1.4 | 4.1 | 1.2 | 14.2 | 4.5 | 6.6 | 1.2 | .009 | ||||
| Troponin I (ng/mL) | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | .477 | ||||
| Creatinine (μmol/L) | 97.8 | 5.4 | 109.0 | 9.0 | 120.8 | 12.9 | 107.1 | 5.2 | .288 | ||||
| BUN (mmol/L) | 7.8 | 0.9 | 9.0 | 1.3 | 11.3 | 2.7 | 8.9 | 0.8 | .356 | ||||
| Sodium (mmol/L) | 139.3 | 0.8 | 139.9 | 0.6 | 139.8 | 0.9 | 139.7 | 0.4 | .843 | ||||
| Hemoglobin (mmol/L) | 8.8 | 0.2 | 9.3 | 0.2 | 8.8 | 0.4 | 9.0 | 0.1 | .204 | ||||
| Male sex | 83% | 87% | 83% | 85% | 0.97 | ||||||||
| Diabetes mellitus type 2 | 42% | 67% | 40% | 53% | 0.35 | ||||||||
| Arterial Hypertension | 58% | 80% | 100% | 76% | 0.13 | ||||||||
| Smoking | 25% | 53% | 20% | 38% | 0.22 | ||||||||
| Hyperlipidemia | 50% | 67% | 80% | 63% | 0.46 | ||||||||
| Adipositas | 73% | 67% | 50% | 66% | 0.64 | ||||||||
| Betablocker | 100% | 100% | 100% | 100% | |||||||||
| ACEI/AT1 | 100% | 100% | 100% | 100% | |||||||||
| Diuretics | 100% | 73% | 100% | 88% | 0.08 | ||||||||
| Aldosterone antagonists | 67% | 73% | 40% | 66% | 0.40 | ||||||||
| NYHA stages | |||||||||||||
| I | 8% | 0% | 0% | 3% | 0.41 | ||||||||
| II | 50% | 47% | 33% | 45% | 0.79 | ||||||||
| III | 42% | 47% | 67% | 48% | 0.60 | ||||||||
| IV | 0% | 0% | 0% | 0% | |||||||||