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Effects of berberine on infarct volume and brain edema in ischemic stroke (n = 5). a Representative images of TTC-stained brain sections of cerebral ischemia–reperfusion mice with berberine pretreatment, vehicle or sham. b Quantification of the infarct volume in the vehicle or berberine pretreatment groups. c Brain water content. Data are presented as the mean ± SD. #P < 0.01 versus the sham group; *P < 0.01 versus the vehicle group
