Fig. 2.

The effects of SAA on the NF-κB and p38 MAPK signaling pathways in 5/6Nx rats. a The protein expression levels of p-IKKα/β, IKKβ, p-IκBα, and IκBα proteins were analyzed by Western blot; b p-IKKα/β protein expression relative to IKKβ protein levels; c p-IκBα protein expression relative to IκBα protein levels; d the protein expression levels of p-NF-κB p65, NF-κB p65, p-p38 MAPK, and p38 MAPK proteins were analyzed by Western blot; e p-NF-κB p65 protein expression relative to NF-κB p65 protein levels; f p-p38 MAPK protein expression relative to p38 MAPK protein levels; g the protein expression levels of ICAM-1 and VCAM-1 proteins were analyzed by Western blot; h ICAM-1 protein expression relative to β-actin protein expression; i VCAM-1 protein expression relative to β-actin protein expression. Data are expressed as the means ± SD (n = 6, all samples were randomly selected from a pool of 10 rats, and then these samples were analyzed). *P < 0.05, **P < 0.01 vs. control group; ^#P < 0.05, ^##P < 0.01 vs. 5/6Nx group