Table 1.
The effects of SAA on biochemical parameters in rats subjected to 5/6Nx
| Groups | Urine protein (mg/24 h) | BUN (mmol/L) | SCr (μmol/L) | TC (mmol/L) | TG (mmol/L) |
|---|---|---|---|---|---|
| Control | 14 ± 1.8 | 14.9 ± 2.1 | 40.6 ± 4.5 | 1.8 ± 0.66 | 0.73 ± 0.14 |
| 5/6Nx | 88.1 ± 13.9** | 56.5 ± 7.4** | 88.5 ± 15.7** | 5.1 ± 1.62** | 1.79 ± 0.18** |
| 5/6Nx+SAA (2.5 mg/kg) | 64.7 ± 16.4 | 44.2 ± 4.3# | 71.9 ± 8.6 | 3.48 ± 1.08 | 1.24 ± 0.18## |
| 5/6Nx+SAA (5 mg/kg) | 53.4 ± 8.3## | 32.7 ± 4## | 57.6 ± 6.7# | 3.19 ± 0.34# | 0.93 ± 0.11## |
| 5/6Nx+SAA (10 mg/kg) | 41.1 ± 18.3## | 27.7 ± 5.5## | 52 ± 13.7# | 2.37 ± 0.51## | 0.83 ± 0.11## |
Data are expressed as the means ± SD (n = 6, all samples were randomly selected from a pool of 10 rats, and then these samples were analyzed). **P < 0.01 vs. control group; #P < 0.05, ##P < 0.01 vs. 5/6Nx group
BUN blood urea nitrogen, SCr serum creatinine, TG triglyceride, TC total cholesterol, SAA salvianolic acid A, 5/6Nx 5/6 nephrectomized