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. 2018 Jun 7;39(7):1176–1188. doi: 10.1038/aps.2018.40

Table 1.

Associations of leptin levels with cardiac and non-cardiac vascular diseases, chronic kidney disease and type 2 diabetes mellitus.

Diseases Leptin levels
CHD Increased leptin levels have been associated with the presence and severity of CHD and HF, as well as with CV morbidity and mortality in CHD patients.
Stroke Increased leptin levels have been associated with the presence and severity of both ischemic and hemorrhagic strokes.
Carotid artery disease Increased leptin levels have been associated with the presence and severity of carotid artery disease.
PAD Increased leptin levels have been associated with the presence of hypertension and T2DM in PAD patients.
AAA Increased leptin levels have been associated with accelerated growth of AAA and ascending aortic aneurysms.
CKD Increased leptin levels have been associated with the presence, severity and progression of CKD.
T2DM Increased leptin levels have been associated with the development of T2DM as well as with micro- and macrovascular diabetic complications.

CHD: coronary heart disease; PAD: peripheral artery disease; AAA: abdominal aortic aneurysm; CKD: chronic kidney disease; T2DM: type 2 diabetes mellitus; HF: heart failure; CV: cardiovascular