Table 1.
Associations of leptin levels with cardiac and non-cardiac vascular diseases, chronic kidney disease and type 2 diabetes mellitus.
Diseases | Leptin levels |
---|---|
CHD | Increased leptin levels have been associated with the presence and severity of CHD and HF, as well as with CV morbidity and mortality in CHD patients. |
Stroke | Increased leptin levels have been associated with the presence and severity of both ischemic and hemorrhagic strokes. |
Carotid artery disease | Increased leptin levels have been associated with the presence and severity of carotid artery disease. |
PAD | Increased leptin levels have been associated with the presence of hypertension and T2DM in PAD patients. |
AAA | Increased leptin levels have been associated with accelerated growth of AAA and ascending aortic aneurysms. |
CKD | Increased leptin levels have been associated with the presence, severity and progression of CKD. |
T2DM | Increased leptin levels have been associated with the development of T2DM as well as with micro- and macrovascular diabetic complications. |
CHD: coronary heart disease; PAD: peripheral artery disease; AAA: abdominal aortic aneurysm; CKD: chronic kidney disease; T2DM: type 2 diabetes mellitus; HF: heart failure; CV: cardiovascular