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Plasma concentration and tissue distribution of docetaxel in A549 xenograft nude mice with or without apatinib treatment. (A) Concentration of docetaxel in tumors. (B) Concentration of docetaxel in plasma. (C) Tissue distribution of docetaxel in the kidney, liver, lung and heart. ** P<0.01 apatinib+docetaxel vs docetaxel.
