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. Author manuscript; available in PMC: 2018 Dec 11.
Published in final edited form as: Proc IEEE Int Symp Biomed Imaging. 2010 Jun 21;2010:101–104. doi: 10.1109/ISBI.2010.5490405

Fig. 1.

Fig. 1

Top: Left hemisphere. Bottom: Right hemisphere. In both cases, the first column represents the name of the segmented structure; the second column gives the p-value assessing the fit of the ACE quantitative genetic model. In the A/C/E analysis, a high p-value means that the model fits well. The third column gives the p-value for the additive genetic factor (p-values below 0.05, uncorrected, show the local statistical significance of the genetic contribution to cortical volume). The fourth column shows a False Discovery Rate (FDR) analysis [2], in which p-values for the additive genetic factors are thresholded at a level that controls the expected false discovery rate at 5%. A statistical threshold of p=0.036 can be applied to controls the FDR at 5%. Here, structures that satisfy this threshold have are given a value of 1, and 0 otherwise. Structures highlighted in bold are among those appearing the FDR-corrected map of heritable brain structures. The colors on the maps are arbitrarily chosen to delineate different segmented regions, and do not encode p-value information.