. Author manuscript; available in PMC: 2019 Dec 15.

Published in final edited form as: J Immunol. 2018 Nov 16;201(12):3569–3579. doi: 10.4049/jimmunol.1500497

Table 1.

Bcl6^hi antigen specific B cell Numbers

Genotype	# of Bcl6^hi Antigen Specific B cells per 10³ Total Antigen Specific B cells^a
Genotype	Naive	Day 2^b	Day 3^b	Day 4^b	Day 6^b
WT	9.9 ± 6.3	6.6 ± 2.2	37.8 ± 9.6	230.1 ± 37.5	363.7 ± 26.8
IL21R-^/-	6.1 ± 3.4	3.9 ± 1.2	15.2 ± 3.2	66.6 ± 13.9^**	46.7 ± 10.1^***
STAT6-^/-	3.4 ± 1.2	2.4 ± 0.9	23.1 ± 4.3	224.8 ± 47.5	106.3 ± 9.0^***
IL21R-^/- STAT6-^/-	3.5 ± 1.8	1.7 ± 2.2	14.5 ± 5.3	41.9 ± 3.9^**	30.0 ± 4.4^***

Antigen specific B cells were defined as GFP⁺ B220⁺ CD4^- splenic mononuclear cells

Days post-immunization with NP-OVA in alum I.P.

Indicated significance based on comparison to WT population at each given time point. Shown is a representative experiment of three independent experiments. Data shown as mean ± SEM. n = 4 or 5.

p < 0.05,

^**

p < 0.01,

^***

p < 0.001.