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. Author manuscript; available in PMC: 2019 Dec 21.
Published in final edited form as: Chem Soc Rev. 2018 Sep 27;47(24):9106–9136. doi: 10.1039/c8cs00537k

Scheme 2.

Scheme 2

Selected bioorthgonal reactions based on azide functionality. (A) The Staudinger ligation. (B) The traceless Staudinger ligation. (C) CuAAC reaction. (D) SPAAC reaction. DBCO is shown as an example for the strained alkyne compound.