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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Am J Med Genet A. 2018 Sep 14;176(11):2404–2418. doi: 10.1002/ajmg.a.40482

Fig. 3: Facial features of individuals with WBS.

Fig. 3:

(A1-2) patient 1 at 2 years of age showing flat supraorbital ridges, depressed nasal bridge, broad nasal tip, overhanging columella, normal philtrum, prominent upper lip, retrognathia and small cupped ears.; (B1-2) patient 2 at 2 years of age with a short forehead, triangular and small face, arched eyebrows, deep-set eyes, flat nasal bridge, short prominent nose with overhanging columella, short philtrum, full lips and retrognathia.; (C1-2) patient 3 at 6 years of age. Note short forehead, small face, deep-set eyes, epicanthic folds, droopy eyelids, depressed nasal bridge, overhanging columella, short philtrum, full lips, and retrognathia.; (D1-2) patient 5 at 5 years of age (D1) and at 6 years of age (D2) with a triangular small face, receding short forehead, prominent eyes, beaked nose, narrow nostrils, overhanging columella, short philtrum, thin lips and retrognathia, posteriorly rotated ears with marked prominence of antihelix and small and attached earlobes with prominent targus.