A) Positive and Negative Predictive Values of ThyroSeq v2 compared to values predicted by Bayes Theorem (Pre-test probability; MSKCC 23%, MCC 18%, CSMC 27%, MSHS 11%). B) Alternative values with NIFTP considered malignant (Pre-test probability; MSKCC 42%, MCC 31%, CSMC 36%, MSHS 17%). MSKCC, Memorial Sloan-Kettering Cancer Center; MCC, Moffitt Cancer Center; CSMC, Cedars-Sinai Medical Center; MSHS, Mount Sinai Health System; PPV, positive predictive value; NPV, negative predictive value.