Recipient characteristic |
Age (years), mean± SD |
68.0± 2.7 |
67.8± 2.6 |
67.8± 2.5 |
67.6± 2.4 |
.001 |
Female, % |
38.9 |
37.2 |
36.9 |
34.0 |
.006 |
BMI, mean± SD |
27.4± 4.9 |
27.9± 5.3 |
28.0± 5.1 |
28.4± 5.1 |
<.001 |
Race, % |
White |
77.7 |
74.1 |
73.8 |
73.8 |
<.001 |
African American |
3.9 |
5.1 |
6.7 |
7.8 |
|
Indication for LT, % |
Hepatitis C virus cirrhosis |
16.5 |
12.6 |
15.8 |
18.1 |
<.001 |
Alcoholic cirrhosis |
12.6 |
14.1 |
12.7 |
13.0 |
|
Non-alcoholic steatohepatitis |
5.8 |
13.0 |
14.2 |
19.5 |
|
Hepatocellular carcinoma |
18.4 |
27.9 |
29.1 |
28.9 |
|
Cholestatic liver disease |
10.0 |
8.3 |
7.8 |
6.7 |
|
Non-cholestatic cirrhosis |
26.4 |
18.2 |
13.8 |
8.6 |
|
MELD, % |
<10 |
3.0 |
1.4 |
0.6 |
0.4 |
<.001 |
10–19 |
28.3 |
20.7 |
12.7 |
11.4 |
|
20–29 |
53.8 |
62.7 |
58.3 |
52.9 |
|
30–39 |
11.1 |
10.6 |
20.2 |
27.5 |
|
≥40 |
1.9 |
3.6 |
6.4 |
6.7 |
|
Status 1/1A |
1.9 |
1.1 |
1.7 |
1.2 |
|
Life support (prior to LT) |
2.8 |
3.1 |
4.7 |
5.3 |
<.001 |
Ascites, % |
2.0 |
2.0 |
2.0 |
1.9 |
.001 |
Albumin (g/dL) |
1.1 |
1.1 |
1.1 |
1.2 |
<.001 |
Portal vein thrombosis, % |
5.0 |
8.9 |
14.3 |
14.6 |
<.001 |
Comorbidities, % |
HIV |
0.1 |
0.1 |
0.1 |
0.2 |
.79 |
Hepatitis C |
27.5 |
27.6 |
30.2 |
32.6 |
<.001 |
Diabetes mellitus |
31.0 |
34.5 |
33.5 |
37.4 |
<.001 |
Liver transplant characteristic |
Cold ischemia time (hours), % |
0–8 |
72.3 |
80.6 |
88.4 |
88.5 |
<.001 |
9–11 |
18.0 |
14.2 |
9.8 |
9.7 |
|
≥12 |
9.7 |
5.2 |
1.8 |
1.8 |
|
ABO incompatible, % |
0.5 |
0.5 |
0.7 |
1.0 |
.08 |
Split graft, % |
1.2 |
1.9 |
1.7 |
1.5 |
.37 |
Donor characteristic |
Age, % |
|
|
|
|
<.001 |
<18 |
6.2 |
6.2 |
5.1 |
5.1 |
|
18–39 |
28.8 |
32.8 |
34.6 |
36.5 |
|
40–49 |
18.7 |
17.5 |
16.9 |
17.1 |
|
50–59 |
19.0 |
18.3 |
20.2 |
20.3 |
|
60–69 |
15.4 |
13.8 |
15.0 |
14.3 |
|
≥70 |
12.0 |
11.5 |
8.2 |
6.7 |
|
Female, % |
44.9 |
40.2 |
43.1 |
40.8 |
.02 |
Race, % |
White |
71.6 |
64.4 |
66.0 |
65.7 |
<.001 |
African American |
14.3 |
17.2 |
19.4 |
18.8 |
|
Donation after cardiac death, % |
4.8 |
6.4 |
5.4 |
7.2 |
.003 |
Hepatitis C, % |
1.2 |
1.8 |
2.3 |
5.3 |
<.001 |