Table 3.

Length of stay, one-year acute rejection, all-cause graft loss, and mortality for older liver transplant (LT) recipients.

Year of LT	Older recipients (N= 8,627)
Length of stay >2 weeks	N	aOR (95% CI) P value
2003–2006	1453	Reference
2007–2009	1544	0.83 (0.71, 0.98) P=.03
2010–06/18/2013	2222	0.73 (0.63, 0.85) P<.001
06/19/2013–2016	3408	0.66 (0.57, 0.76) P<.001
One-year acute rejection	N	aOR (95% CI) P value
2003–2006	1453	Reference
2007–2009	1544	1.00 (0.79, 1.27) P=.99
2010–06/18/2013	2222	0.74 (0.58, 0.93) P=.01
06/19/2013–2016	3408	0.70 (0.56, 0.88) P=.002
All-cause graft loss	N	aHR (95% CI) P value
2003–2006	1453	Reference
2007–2009	1544	0.83 (0.75, 0.92) P=.001
2010–06/18/2013	2222	0.68 (0.61, 0.75) P<.001
06/19/2013–2016	3408	0.46 (0.40, 0.52) P<.001
Mortality	N	aHR (95% CI) P value
2003–2006	1453	Reference
2007–2009	1544	0.83 (0.75, 0.93) P=0.001
2010–06/18/2013	2222	0.67 (0.60, 0.75) P<.001
06/19/2013–2016	3408	0.43 (0.38, 0.49) P<.001

Adjusted odds ratios (aORs) of one-year acute rejection loss and length of stay >2 weeks (relative to 2003–2006) in older were estimated using logistic regression. Adjusted hazard ratios (aHRs) of mortality and graft loss (relative to 2003–2006) in older recipients were estimated using Cox models. aHRs and aORs were adjusted for recipient factors (sex, age, race, body mass index (BMI), primary diagnosis, life support, hepatocellular carcinoma (HCC), non-HCC malignancy, hepatitis C virus (HCV), HIV status, diabetic, primary insurance, portal vein thrombosis, and split LT), and donor factors (age, race, BMI, HCV, donation after cardiac death (DCD), ABO compatibility, as well as donor and recipient geography).

^*The two latest time periods were split at 6/18/2103 after the allocation policy implementation of Share35. This policy increases regional liver allograft offers to patients with MELD score ≥35.