Table 3.
Factors associated with preferred role for decisions related to return of results from whole genome sequencing as part of research.
| Preferred Role (passive as reference) | Active Role | p-value | Collaborative Role | p-value |
|---|---|---|---|---|
| Bivariate Analysis | ||||
| OR (95% Cl) | p-value | OR (95% Cl) | p-value | |
| General perception of health: Very good/Excellent |
2.141 (1.418–3.233) |
<0.001 | 1.877 (1.216–2.897) |
0.005 |
| Genetic self-efficacy | 1.285 (1.066–1.549) |
0.009 | 1.160 (0.953–1.412) |
0.138 |
| Age | 1.055 (1.027–1.084) |
<0.001 | 1.063 (1.034–1.093) |
<0.001 |
| Age at diagnosis | 1.062 (1.013–1.113) |
0.013 | 1.092 (1.037–1.150) |
<0.001 |
| Time since diagnosis | 1.072 (1.032–1.113) |
<0.001 | 1.074 (1.034–1.117) |
<0.001 |
| Subjective numeracy scale | 1.317 (1.043–1.661) |
0.021 | 1.061 (0.834–1.351) |
0.630 |
| Multivariable Analysis1 | ||||
|---|---|---|---|---|
| OR (95% Cl) | p-value | OR (95% Cl) | p-value | |
| General perception of health: Very good/Excellent |
1.858 (1.199–2.878) |
0.006 | 1.673 (1.051 −2.665) |
0.030 |
| Age at diagnosis | 1.063 (1.011 −1.117) |
0.016 | 1.089 (1.032–1.149) |
0.002 |
| Time since diagnosis | 1.071 (1.031 −1.113) |
<0.001 | 1.073 (1.032–1.117) |
<0.001 |
| Subjective numeracy preference subscale | 1.309 (1.042–1.646) |
0.021 | 1.095 (0.863–1.390) |
0.454 |
1
Model controlling for genetic causal belief and biological children