TABLE 1.
GN (n=803) |
HTN (n=442) |
DM (n=947) |
PKD (n=549) |
|
---|---|---|---|---|
Age (years), mean | 45.3 ± 13.2 | 53.2 ± 12.4* | 54.8 ± 10.1* | 52.7 ± 9.1* |
Female, n (%) | 340 (42%) | 125 (28%)* | 322 (34%)* | 256 (47%) |
White ethnicity, n (%) | 646 (80%) | 275 (62%)* | 788 (83%) | 510 (93%)* |
Pre-transplant dialysis, n (%) | 592 (74%) | 378 (86%)* | 804 (85%)* | 324 (59%)* |
Dialysis duration prior to transplant (months), mean |
19.6 ± 22.9 | 26.0 ± 25.1* | 20.7 ± 20.0* | 14.0 ± 24.8* |
Panel reactive antibody >10%, n (%) | 71 (19%) | 37 (17%) | 82 (17%) | 50 (19%) |
Deceased donor, n (%) | 422 (53%) | 327 (74%)* | 623 (66%)* | 301 (55%) |
Donor age (years), mean | 41.8 ± 14.3 | 43.7 ± 15.1* | 43.9 ± 14.8* | 43.6 ± 14.3* |
HLA mismatch >2, n (%) | 568 (71%) | 352 (80%)* | 675 (71%) | 427 (78%)* |
Delayed graft function, n (%) | 111 (14%) | 115 (26%)* | 227 (24%)* | 74 (13%) |
Induction, n (%) • Alemtuzumab • Basiliximab • Thymoglobulin • None |
114 (14%) 414 (52%) 131 (16%) 144 (18%) |
64 (15%) 226 (51%) 92 (21%) 60 (14%) |
168 (18%) 459 (48%) 200 (21%) 120 (13%) |
82 (15%) 323 (59%) 84 (15%) 60 (11%) |
Maintenance immunosuppression, n (%) • Prednisone • CNI • Mycophenolate |
801 (100%) 730 (91%) 709 (88%) |
442 (100%) 397 (90%) 394 (89%) |
947 (100%) 844 (89%) 857 (90%) |
549 (100%) 495 (90%) 506 (92%)* |
GN, glomerulonephritis; HTN, hypertension; DM, diabetes mellitus; PKD, polycystic kidney disease; HLA, human leukocyte antigen; CNI, calcineurin inhibitor
P<0.05 compared to GN