Table 4.

Efficacy of Existing LT4 Prediction Schemes and a Novel Poisson Dosing Algorithm

Scheme	% Euthyroid doses	% Dose errors > 25 μg	% Hypothyroid	% Hyperthyroid
1.6 μg/kg/day	51.3%	26.9%	16.4%	32.3%
Cunningham et al.	27.4%	46.5%	7.0%	65.6%
Olubowale et al.	43.5%	25.9%	15.7%	40.8%
Mistry et al.	40.1%	40.0%	9.2%	50.7%
Ojomo et al.	60.9%	23.1%	16.1%	23.1%
Jin et al.	53.2%	25.1%	24.4%	22.4%
Di Donna et al.	60.0%	21.6%	18.4%	21.6%
Elfenbein et al.	60.2%	22.1%	17.4%	22.4%
Poisson Dosing	64.8%	19.1%	15.7%	19.5%