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. 2018 Oct 8;25(6):655–665. doi: 10.1093/dnares/dsy032

Table 1.

Distribution of protein families associated with immune response

Pfam Domain Sgl Cgi Pfu Pye Mph Bpl Lgi Aca Obi Lan Cte
PF00335 Tetraspanin 63 54 53 52 4 42 39 49 31 43 50
PF00061 Lipocalin 12 13 14 11 1 11 14 17 0 17 2
PF02798 GST_N 33 25 37 29 2 23 24 56 22 44 22
PF00255 GSHPx 6 8 9 6 1 7 4 3 4 10 3
PF08210 APOBEC_N 7 2 2 1 1 1 0 0 0 6 0
PF00080 Sod_Cu 8 10 8 8 2 6 9 9 4 6 6
PF01823 MACPF 20 13 9 5 10 13 4 3 0 8 1
PF11648 RIG-I_C-RD 9 8 6 5 2 12 3 5 1 6 3
PF02898 NO_synthase 1 1 7 1 1 2 1 3 1 3 2
PF16673 TRAF_BIRC3_bd 2 2 2 1 1 1 0 0 0 0 1
  Total 161 136 147 119 25 118 98 145 63 143 90

Number of proteins containing the specific Pfam domain for each family. GST_N, glutathione S-transferase; GSHPx, glutathione peroxidase; APOBEC_N, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like N-terminal domain, N-terminal domain; Sod_Cu, Copper/zinc superoxide dismutase (SODC); MACPF, membrane attack complex/perforin (MACPF) domain; RIG-I_C-RD, C-terminal domain of RIG-I; NO_synthase, nitric oxide synthase, oxygenase domain; TRAF_BIRC3_bd, TNF receptor-associated factor BIRC3 binding domain.