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. 2018 Sep 4;25(6):597–617. doi: 10.1093/dnares/dsy028

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© The Author(s) 2018. Published by Oxford University Press on behalf of Kazusa DNA Research Institute.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 4. — Representative terpenoid biosynthesis pathway with cognate heat maps for transcript levels of genes from S. guaranitica transcriptome data with substrates and products, coloured arrows connect substrates to their corresponding products. Green/red colour-coded heat maps represent relative transcript levels of different terpenoid genes determined by Illumina HiSeq 2000 sequencing; red, up-regulated; green, down-regulated. Transcript levels data represent by FPKM: fragments per kilobase of transcripts per million mapped fragments. MeV, multi-experiment Viewer software was used to depict transcript levels. DXS, 1-deoxy-d-xylulose-5-phosphate synthase; DXR, 1-deoxy-d-xylulose-5-phosphate reductoisomerase; MCT, 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase; ISPF, 2-C-methyl-d-erythritol 2, 4-cyclodiphos-phate synthase; HDS, (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase; HDR, 4-hydroxy-3-methylbut-2-enyl diphosphate reductases; IDI, isopentenyl-diphosphate delta isomerase; AACT, acetyl-CoA C-acetyl transferase; HMGS, hydroxyl methyl glutaryl-CoA synthase; HMGR, hydroxymethyl glutaryl-CoA reductase (NADPH); MVK, mevalonate kinase; PMK, phospho-mevalonate kinase; GPPS, geranyl diphosphate synthase; FPPS, farnesyl pyrophosphate synthase; GGPS, geranylgeranyl diphosphate synthase, type II; CINS, 1,8-cineole synthase; MYS, myrcene/ocimene synthase; LINS, (3S)-linalool synthase; NEOM, (+)-neomenthol dehydrogenase; SABI, (+)-sabinene synthase; TPS6, (-)-germacrene d synthase; AMS, beta-amyrin synthase; FARNESOL, farnesol dehydrogenase; SEQ, squalene monooxygenase; HUMS, α-humulene/β-caryophyllene synthase; FAR, farnesyl-diphosphate farnesyltransferase; GA2, gibberellin 2-oxidase; GA20, gibberellin 20-oxidase; E-KS, ent-kaurene synthase; MAS, momilactone-A synthase; GA3, gibberellin 3-beta-dioxygenase; E-KIA, ent-iso-kaurene C2-hydroxylase; E-KIH, ent-kaurenoic acid hydroxylase; E-CDS, ent-copalyl diphosphate synthase.