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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Brain Behav Immun. 2018 Sep 11;74:291–295. doi: 10.1016/j.bbi.2018.09.013

Figure 1. Bioinformatic analysis of transcription factor activity.

Figure 1.

A.) Prevalence of NF-kB and IRF transcription factor-binding motifs(TFBMs) in promoters of genes up-regulated in association with cancer-related fatigue vs.down-regulated. Data represent log2 ratios (null value=1.0-fold=0.0 log2)averaged over 9 combinations of promoter length and TFBM detection stringency. B.) Prevalence of NF-kB and IRF TFBMs in promoters of genes up-regulated in HPV-related HNC vs. down-regulated ***p<.001,**p<.01,*p<.05