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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Biol Psychiatry. 2018 Jun 21;85(1):49–59. doi: 10.1016/j.biopsych.2018.06.007

Table 2. Coordinates of significant brain areas where resting-state functional connectivity with left motor cortex were significantly related with cortical inhibition and overall symptoms in schizophrenia spectrum disorder patients.

Talairach
(x, y, z) mm
Brodmann
area
Cluster
size
r
SICI related rsFC in schizophrenia
  Left middle prefrontal gyrus (–25, 47, –2) 10/11 206 −0.81*
  Left middle Cerebellum (VIII) (–15, –66, –34) n/a 222 -0.75*
  Right middle prefrontal gyrus (39, 39, –6) 10/11 427 -0.87*
  Right Insula (46, 9, –5) 13 219 -0.77*
BPRS related rsFC in schizophrenia
  Left superior occipital gyrus (–17, –85, 41) 19 656 0.79*
  Left postcentral gyrus (–35, –29, 47) 3/4 601 0.83*
  Left middle prefrontal gyrus (–20, 54, –4) 10/11 546 -0.84*
  Left precentral gyrus (–30, –14, 60) 4/6 256 0.73*
  Left middle occipital gyrus (–18, –97, 9) 18 246 0.78*
  Left inferior frontal gyrus (–50, 6, 24) 9/44 210 0.73*
  Left cerebellum (VI) (–30, –43, –27) n/a 204 -0.81*
  Right superior occipital gyrus (19, –86, 33) 7/19 808 0.74*
  Right superior parietal lobule (28, –65, 52) 7 754 0.81*
  Right postcentral gyrus (33, –30, 48) 3/4 535 0.86*
  Right anterior cingulate (10, 36, 25) 32 358 -0.83*
  Right cerebellum (VI) (22, –76, –12) n/a 328 0.75*
  Right precentral gyrus (40, –18, 60) 4/6 251 0.81*

r: correlation coefficients between behavioral, i.e., Brief Psychiatric Rating Scale total score (BPRS) and short-interval intracortical inhibition (SICI), and the mean resting-state functional connectivities (rsFCs) between motor cortex and each cluster.

*

corrected p<0.05. Data for healthy controls are in Supplementary Table S1.