Table 3.
Marginal Cox Regression Models Predicting Isolated-Asthma, Isolated-COPD, and Asthma/COPD Overlap
| Variable | Asthma/COPD Overlap vs Neither |
Isolated-Asthma vs Neither |
Isolated-COPD vs Neither |
||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P Value | HR | 95% CI | P Value | HR | 95% CI | P Value | |
| Eosinophils ≥ 300 cells/μLa | 1.85 | 1.16-2.95 | .009 | 0.93 | 0.63-1.36 | .69 | 1.16 | 0.82-1.64 | .39 |
| Accelerated FEV1 decline | 2.17 | 1.40-3.35 | < .001 | 2.12 | 1.54-2.91 | < .001 | 2.18 | 1.59-2.99 | < .001 |
| Ever-smoker | 0.92 | 0.58-1.44 | .70 | 0.77 | 0.56-1.05 | .09 | 1.60 | 1.18-2.17 | .003 |
| WTC exposure morning of 9/11 | 1.40 | 0.84-2.32 | .19 | 1.58 | 1.14-2.20 | .006 | 0.86 | 0.59-1.26 | .44 |
The total N value was 2,124 due to missing covariates. Data were adjusted for age, race, BMI, and first post-9/11 FEV1/FVC measurement. HR = hazard ratio. See Table 1 legend for expansion of other abbreviation.
a
First post-9/11 measurement.