Table 2.

Differences between groups in terms of immunohistochemical staining and in situ hybridization for the detection of cleaved caspase 3 in liver.

Groups	Caspase 3
Control	0.20 ± 0.002a
12 mg/kg 24 h	0.40 ± 0.024a
12 mg/kg 48 h	0.60 ± 0.04a
12 mg/kg 72 h	0.20 ± 0.008a
24 mg/kg 24 h	0.40 ± 0.014a
24 mg/kg 48 h	0.60 ± 0.029a
24 mg/kg 72 h	0.40 ± 0.011a
36 mg/kg 24 h	0.40 ± 0.024a
36 mg/kg 48 h	2.40 ± 0.13b
36 mg/kg 72 h	2.60 ± 0.25b

Means with the same letter, per each column, are not significantly different according to Mann-Whitney U test, p ≤ 0.05, n = 5.