Table 1.
Characteristics for PPCOS II participants who ovulated with tubal patency confirmed by SIS versus HSG and for all participants who ovulated
| Variable | SIS | HSG | All patients | P value* |
|---|---|---|---|---|
| N | 414 | 187 | 619** | |
| Age (year) | 28.7 ± 4.2 | 29.5 ± 4.0 | 28.9 ± 4.1 | 0.033 |
| Treatment | 0.964 | |||
| Clomiphene | 194 (46.9) | 88 (47.1) | 288 (46.5) | |
| Letrozole | 220 (53.1) | 99 (52.9) | 331 (53.5) | |
| BMI (kg/m2) | 35.3 ± 9.6 | 32.5 ± 8.3 | 34.4 ± 9.3 | < 0.001 |
| Race | 0.416 | |||
| White | 322 (77.8) | 145 (77.5) | 482 (77.9) | |
| Black or African-American | 58 (14.0) | 28 (15.0) | 87 (14.0) | |
| Asian | 17 (4.1) | 5 (2.7) | 23 (3.7) | |
| American Indian or Alaska Native | 2 (0.5) | 4 (2.1) | 6 (1.0) | |
| Native Hawaiian or Pacific Islander | 1 (0.2) | 0 (0.0) | 1 (0.2) | |
| Mixed race | 14 (3.4) | 5 (2.7) | 20 (3.2) | |
| Ethnic group | 0.097 | |||
| Not Hispanic or Latino | 346 (83.6) | 166 (88.8) | 529 (85.5) | |
| Hispanic or Latino | 68 (16.4) | 21 (11.2) | 90 (14.5) | |
| Months attempting conception | 42.5 ± 38.7 | 37.0 ± 31.2 | 40.2 ± 36.3 | 0.095 |
| Prior pregnancy | 147 (35.5) | 72 (38.5) | 235(38.0) | 0.480 |
| Prior pregnancy loss | 89 (21.5) | 54 (28.9) | 150 (24.2) | 0.049 |
| Prior live birth | 87 (21.0) | 32 (17.0) | 129 (20.8) | 0.266 |
| AMH (ng/ml) | 7.0 ± 5.5 | 9.0 ± 8.2 | 7.6 ± 6.5 | < 0.001 |
| Total antral follicle count | 45.4 ± 25.4 | 46.6 ± 25.6 | 45.5 ± 25.3 | 0.579 |
| Total testosterone (ng/dl) | 53.6 ± 29.6 | 54.6 ± 28.1 | 53.6 ± 28.8 | 0.718 |
| Endometrial thickness (mm) | 6.5 ± 2.8 | 6.7 ± 2.7 | 6.6 ± 2.8 | 0.524 |
| Estradiol level (pg/ml) | 56.0 ± 37.8 | 57.2 ± 33.6 | 56.2 ± 36.3 | 0.719 |
| History of smoking | 0.059 | |||
| Never smoked | 243 (58.7) | 118 (63.1) | 369 (59.6) | |
| Current smoking | 65 (15.7) | 16 (8.6) | 83 (13.4) | |
| Quit smoking | 106 (25.6) | 53 (28.3) | 167 (27.0) | |
| Education | 0.551 | |||
| High school graduate or less | 94 (22.7) | 36 (19.3) | 135 (21.8) | |
| College graduate or some college | 267 (64.5) | 123 (65.8) | 402 (64.9) | |
| Graduate degree | 53 (12.8) | 28 (15.0) | 82 (13.3) | |
| Income | 0.010 | |||
| < $50,000 | 179 (43.2) | 63 (33.7) | 248 (40.1) | |
| ≥ $50,000 | 173 (41.8) | 103 (55.1) | 286 (46.2) | |
| Wish to not answer | 62 (15.0) | 21 (11.2) | 85 (13.7) | |
| Partner sperm concentration (million/ml) | 80.4 ± 70.7 | 82.1 ± 75.7 | 80.3 ± 71.6 | 0.791 |
Values are mean ± standard deviation or n (%)
*P value for significance of difference between SIS vs. HSG groups only
**Includes only 619 patients who ovulated