Table 3.
Polymorphism frequency in Cdx2, FokI, BsmI, ApaI, TaqI region of VDR gene in patients and controls and association with osteosarcoma risk.
VDR aleli | Hasta | Kontrol | OR | %95 CI | p | |
---|---|---|---|---|---|---|
FoxI | Wild | 36 (%62.0) | 37 (%49.3) | 1.68 | 0.83–3.37 | 0.14 |
Heterozygous polimorphic | 18 (%31) | 32 (%42.7) | 0.60 | 0.29–1.24 | 0.17 | |
Homozygous polimorphic | 4 (%6.9) | 6 (%8.0) | 0.85 | 0.22–3.17 | 0.81 | |
Bsm1 | Wild | 16 (%27.6) | 28 (%37.3) | 0.63 | 0.30–1.34 | 0.23 |
Heterozygous polimorphic | 35 (%60.3) | 38 (%50.7) | 1.48 | 0.74–2.96 | 0.26 | |
Homozygous polimorphic | 7 (%12.1) | 9 (%1.02) | 1.07 | 0.35–2.88 | 0.99 | |
Apa1 | Wild | 19 (%32.8) | 26 (%34.7) | 0.97 | 0.47–2.01 | 0.94 |
Heterozygous polimorphic | 31 (%53.4) | 33 (%44.0) | 1.46 | 0.73–2.90 | 0.28 | |
Homozygous polimorphic | 8 (%13.8) | 16 (%21.3) | 0.59 | 2.23–1.49 | 0.26 | |
Taq1 | Wild | 22 (%37.9) | 31 (%41.3) | 0.86 | 0.43–1.75 | 0.69 |
Heterozygous polimorphic | 33 (%56.9) | 37 (%49.3) | 1.35 | 0.38–2.70 | 0.38 | |
Homozygous polimorphic | 3 (%5.2) | 7 (%9.3) | 0.53 | 0.13–2.14 | 0.36 | |
Cdx2 | Wild | 36 (%62.1) | 48 (%64.0) | 0.92 | 0.45–1.87 | 0.82 |
Heterozygous polimorphic | 20 (%34.5) | 24 (%32.0) | 1.12 | 0.54–2.31 | 0.76 | |
Homozygous polimorphic | 2 (%3.4) | 3 (%4.0) | 0.85 | 0.13–2.31 | 0.87 |