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. 2018 Dec 11;8:17768. doi: 10.1038/s41598-018-35675-y

Table 2.

Solutions of Problems (1) and (2) with x = [d].

Objective Function Optimizer Optimum
Minimize Tumor Diameter (normalized) d* = 190 nm TD* = 0.683
Maximize Tumor Nanoparticle Fraction d* = 147 nm TNP* = 0.137