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. 2018 Dec 11;9:5124. doi: 10.1038/s41467-018-07617-9

Table 3.

Cancer mortality 1961–2015 in G2 men by paternal grandparents’ harvest exposures in SGP: hazard ratios with 95% confidence limits (in brackets) based on Cox regression

All cancers
  Access to food Model 1 Model 2
 Paternal grandmother
 Good 1.09 [0.39, 3.00] 1.20 [0.40, 3.62]
 Intermediate 1.00 ref. 1.00 ref.
 Poor 1.37 [0.59, 3.18] 1.45 [0.63, 3.34]
Paternal grandfather
 Good 3.35 a [1.95, 5.76] 3.44 b [1.87, 6.34]
 Intermediate 1.00 ref. 1.00 ref.
 Poor 0.65 [0.20, 2.06] 0.63 [0.20, 1.99]
 Observations 3224 3224
 Number of deaths 117 117
Cancers not related to smoking
Paternal grandmother
 Good 0.00 [0.00] 0.00 [0.00,]
 Intermediate 1.00 ref. 1.00 ref.
 Poor 1.01 [0.31, 3.28] 1.13 [0.35, 3.65]
Paternal grandfather
 Good 3.51 c [1.77, 6.97] 4.39 d [2.02, 9.53]
 Intermediate 1.00 ref. 1.00 ref.
 Poor 0.78 [0.19, 3.26] 0.86 [0.21, 3.52]
 Observations 3224 3224
 Number of deaths 70 70

Statistically significant estimates (95% CI) in bold type

Model 1: Adjusted for G2 birth year, sibship size and sibling order, father’s harvest exposure in SGP, social class, income and education, and any parental death before age 18

Model 2: + linear trends for grandparents birth years, with confidence limits based on sibling cluster robust standard errors

aInteraction by gender: p= 0.006

bInteraction by gender: p = 0.005

cInteraction by gender: p = 0.013

dInteraction by gender: p = 0.009