Table 1.

Percentage ratings for new medicines and new indications introduced in France between 2010 to 2015 [Adapted from (2, 31, 32)].

Prescrire ratings/criteria	2010	2011	2012	2013	2014	2015
Total number of new medicines/new indications	97	92	82	90	87	87
Innovative medicine/ real therapeutic advance	1%	0%	1%	0%	3%	3%
Offers an advantage over current standards	3%	3%	4%	7%	6%	6%
Possibly helpful, minimal or no clinical advantage compared to existing standard treatments	73%	72%	68%	66%	58%	67%
Others including not being seen as acceptable due to known or suspected serious adverse events as well as uncertain, unproven or limited effectiveness. In addition, judgement reserved regarding the possible level of innovation due to insufficient data available	23%	25%	27%	27%	33%	24%