TABLE 1.

Echocardiography for CCC mice

Uninf, n = 9; CCC-Veh, n = 8; CCC-sPDNF, n = 10. Mean + S.D. is indicated for each parameter.

	Uninf	CCC-Veh	CCC-sPDNF
End diastolic diameter (mm)	3.637 ± 0.30	4.629 ± 1.03a	3.489 ± 0.49b
End systolic diameter (mm)	2.620 ± 0.43	3.233 ± 1.06	2.142 ± 0.55b
Anterior wall thickness (mm)	0.780 ± 0.13	0.771 ± 0.19	0.776 ± 0.10
Posterior wall thickness (mm)	0.879 ± 0.20	0.864 ± 0.27	0.872 ± 0.25
Heart rate (bpm)	438.9 ± 52.4	226.3 ± 124.2c	347.8 ± 131.0
Ejection fraction (%)	54.58 ± 12.26	58.59 ± 11.05	68.69 ± 15.06
Fractional shortening (%)	28.24 ± 8.35	31.20 ± 6.72	39.13 ± 12.27
LV mass (mg)	106.23 ± 22.57	164.98 ± 89.04	97.96 ± 22.54d

bpm, beats per minute.

^aP < 0.05, Uninf vs. CCC-Veh.

^bP < 0.01, CCC-Veh vs. CCC-sPDNF.

^cP < 0.01, Uninf vs. CCC-Veh;

^dP < 0.05, CCC-Veh vs. CCC-sPDNF.