Table 2.

Sensitivity of primary myeloma cells to MV-GFP

Sample	Status	del(17p), %	CD138+, %	CD46 MFIR	Death, %	GFP, %	GFP MFIR
1	MM	0	13	46	58	54	10
2	PCL	0	30	47	65	68	10
3	PCL	0	34	202	46	96	19
4	PCL	0	7	36	47	42	6
5	PCL	0	16	60	76	50	14
6	MM	0	19	300	49	20	10
7	MM	0	60	353	40	80	14
8	PCL	0	63	87	67	91	31
9	PE	0	73	22	41	26	13
10	MM	11	7	100	76	62	9
11	PCL	88	40	237	78	58	16
12	PCL	89	29	200	38	53	17
13	PCL	94	41	26	58	90	6
14	PCL	100	21	124	77	94	17

CD46 expression was assessed in double staining with anti-CD138 mAb after isolation of mononuclear cells. Total mononuclear cells were incubated for 4 days with MV-GFP (MOI = 1). GFP expression in CD138⁺ cells represents the percentage of positive cells and the fluorescence intensity of the positive population. Cell death was determined by the percentage of loss of CD138⁺ cells. MFIR, CD46, and control mean fluorescence intensity values are provided in supplemental Table 1B.

PE, pleural effusion.