Table 1.

LCP-SFX data collection parameters and statistics

Receptor/ ligand	5-HT2B/ Erg	ΔCRD-SMO/ cyclopamine	δ-OR/ DIPP-NH2	AT1R/ ZD7155	AT2R/ Cpd 1		Rho-Arr	GCGR/ NNC0640- Fab	SMO/ TC114	A2AAR/ ZM24138 5	5-HT2B/ Erg-Fab
PDB code	4NC3	4O9R	4RWD	4YAY	5UNF	5UNG	4ZWJ	5XEZ	5V56	5K2C*	5TUD
Resolution (Å)	2.8	3.4 / 3.2 / 4.0	2.7	2.9	2.8	2.8	3.8 / 3.8 / 3.3	3.0	2.9	1.9	3.0
Spacegroup	C2221	P21	C2	C2	P21	P21221	P212121	P21	P21	C2221	P21
Crystal size (μm)	5×5×5	10×2×2	5×2×2	10×2×2	5×2×2		10×2×2	~5	5×5×2	5×5×2	1-10
Data acquisition time (min)	590	490	275	385	375		700	140	300	135	260
Flow rate (μL/min)	0.17	0.17	0.17	0.17	0.22		0.2	0.2	0.2	0.22	0.2
Sample volume used (μl)	100	85	50	65	85		140	30	60	30	55
No. of collected images	4,217,508	3,510,525	1,967,539	2,764,739	2,701,530		~5,000,000	~1,000,000	2,102,907	948,961	1,877,040
No. of indexed images	32,819	66,165	36,083	73,130	22,774	15,804	18,864	57,573	65,560	72,735	52,291
% indexed images	0.78	1.9	1.8	2.6	0.84	0.59	0.38	5.8	3.1	7.7	2.8
Total amount of protein used (μg)	300	500	300	292	190		800	115	400	270	420
Protein consumption per 10,000 indexed images (μg)	90	75	85	40	50		425	20	60	37	80
Reference	(65)	(104)	(30)	(114)	(112)		(51)	(113)	(116)	(7)	(47)