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MEA activity from NDM and BPH media on BMT and MCS MEAs. (A) Percentage of active electrodes per network (spike frequency >0.04 Hz). Higher percentages of electrodes were active in BPH on both MEA types. (B) Median spike frequency in active electrodes. (C) Median burst count over 10 min. (D) Spikes per burst median. Measurement 1 = 6 days, 2 = 11 days, 3 = 13 days, 4 = 18 days, and 5 = 19–20 days in adherent culture. Median and interquartile ranges are shown.
