Table 1.
Independent Variables | Symbol | Levels | ||
---|---|---|---|---|
Low (−1) | Medium (0) | High (+1) | ||
Grafting yield (%) | A | 30 | 40 | 50 |
QCS: TPP (weight ratio) | B | 5:1 | 10:1 | 15:1 |
QCS: Genipin (weight ratio) | C | 20:1 | 40:1 | 60:1 |
Dependent Variables | Symbol | Constraints | ||
Particle size (nm) | Y 1 | <200 | ||
PDI | Y 2 | <0.3 | ||
Zeta potential (mV) | Y 3 | |||
Encapsulation efficiency (%) | Y 4 | Maximize |