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. Author manuscript; available in PMC: 2018 Dec 12.
Published in final edited form as: Sci Transl Med. 2015 Sep 23;7(306):306ra151. doi: 10.1126/scitranslmed.aab1720

Figure 3. Preclinical evaluation of a candidate JCV VLP vaccine.

Figure 3.

Mice were given an intramuscular injection of VLPs based on the JCV genotype indicated in each row label. Four weeks later, sera from the mice were tested for neutralization of various pseudoviruses indicated in column labels. Numerical values represent EC50 neutralizing titers. Error represents standard deviation for independent neutralization assays of sera from five replicate mice. Pre-immune sera were non-neutralizing at a 1:100 dilution.