Fig. 1.

ccfDNA yield in K2-EDTA blood and correlation to white blood cell (WBC) count. a Yield of ccfDNA per milliliter plasma from K2-EDTA blood quantified with Qubit 2.0 (Thermo Fisher). Blood samples from 152 healthy donors were processed within 2 h after venipuncture and ccfDNA isolated with the QIAsymphony DSP Circulating DNA Kit (QIAGEN); depicted is the scatter plot with mean and standard deviation. b Correlation between ccfDNA yield per milliliter EDTA plasma plotted and WBC count; depicted are trend line and R-squared value