Table 1.
Findings | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Article | Number of patients with Zika virus infection | Cerebral volume reduction | Malformation of cortical development | Type of calcification | Location of calcifications | |||||||
Cortico-subcortical junction | Basal ganglia | Thalamus | Brainstem and cerebellum | Ventriculomegaly | Occipital bone prominence | Cerebellar hypoplasia | ||||||
Punctate | Coarse | |||||||||||
Hazin et al.(9) | 7 confirmed | Not | 23 (100%) | 72-100% | - | 53-86% | 57-65% | 39-43% | 0 | 23 (100%) | Not | 17 (74%) |
16 presumed | mentioned | mentioned | ||||||||||
Aragão et al.(10) | 6 confirmed | 20 (91%) | 21 (95%) | Majority | - | 23 (100%) | 13 (59%) | 0 | Brainstem | 19 (86%) | 7 (30%) | 11 (50%) |
17 presumed | 8 (35%) | |||||||||||
Cerebellum | ||||||||||||
11 (50%) | ||||||||||||
Cavalheiro et al.(11) | 13 presumed | 13 (100%) | 13 (100%) | 0 | 12 (92.3%) | 12 (92.3%) | 12 (92.3%) | 0 | 0 | 13 (100%) | 13 (100%) | 0 |
This article | 16 confirmed | 13 (81.2%) | 13 (81.2%) | 9 (56.2%) | 7 (43.7%) | 16 (100%) | 2 (12.5%) | 4 (25%) | 2 (12.5%) | 15 (93.7%) | 9 (56.2%) | 3 (18.7%) |