Table 2.

Neuropsychological tests and questionnaires

Domain or goal	Assessment/questionnaires	Duration (min)
Cognitive functioning
Overall cognitive functioning	Researcher subjective impression of cognitive health (see “Methods”)	0
	Mini–Mental State Examination [26, 86]	5
	National Adult Reading Testa [88–89]	3
	Telephone Interview Cognitive Status—Modified (TICS-M)d [90]
Memory	CERAD 10-word list—immediate and delayed recall [91]	15
	Visual Association Test—Memory [92]	5
	Rivermead Behavioral Memory Test (RBMT)b immediate and delayed recall [93, 94]	6
Attention	Digit Span—forwards [96–97]	3
	Trail Making Test A [98, 99]	NA
Executive functions	Digit Span—backwards [96–97]	3
	Letter Fluency—DAT [101–104]	2
	BADS—subtest Key Search [105, 106]	3
	BADS—subtest Rule Shift Cards [105, 106]	3
	Trail Making Test B [98, 99]	10
	Amsterdam Dementia Screening Test—Meander figure [107]	2
Language	Category Fluency—Animals [100, 101, 108]	2
	Visual Association Test—Naming [92]	1
Visuo-spatial functioning/construction	CAMDEX-R/N CAMCOG—figure copying [109, 110]	3
	Clock Drawing Test [111, 112]	2
	Visual Object and Space Perception (VOSP) Batteryb—subtest Number Location [113]	3
Depression, ADL, sleep, lifestyle, geriatric impairments
Depressive symptoms	Geriatric Depression Scale-15 (GDS) [29]	4
(Instrumental) Activities of daily living	Informant Questionnaire on Cognitive Decline in the elderly short form (IQ-CODE) [30, 31]	3
	Barthel Index [27, 115–116]	3
Lifetime cognitively stimulating experience	Lifetime Cognitive Activity Scalea [34, 35]	5
Sleep quality	Pittsburgh Sleep Quality Indexa (PSQI) [28]	5
Geriatric impairments	Researcher subjective impression of sight, hearing, mobility (“Methods”)	0

^aOnly administered at baseline, ^b In 100-plus Study-phase 1 only, ^c Included with the confirmation letter of study-inclusion, collected during the first baseline visit, ^d Only administered during half yearly-follow up of brain donors and yearly follow-up of siblings