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. Author manuscript; available in PMC: 2018 Dec 12.
Published in final edited form as: Crit Rev Biochem Mol Biol. 2010 Dec;45(6):520–534. doi: 10.3109/10409238.2010.513375

Fig. 1.

Fig. 1

Diagrams of topoisomerization and site-specific recombination. (a) DNA Topoisomerization by changing supercoils or decatenation of linked DNA circles. (b) Site-specific recombinases catalyze DNA integration, deletion (also called excision or resolution), and inversion. These reactions require two specific DNA sequences shown as arrows and negative supercols as the energy source. The color versions of all figure are available online.