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. Author manuscript; available in PMC: 2019 Sep 27.
Published in final edited form as: J Med Chem. 2018 Sep 7;61(18):8299–8320. doi: 10.1021/acs.jmedchem.8b00838

Figure 8.

Figure 8.

Inhibition of ENaC activity by amiloride 4, HMA 5 and 6-substituted analogs 11, 18, 25, and 26 in transfected HEK-293 cells. All compounds were present at 10 μM. Data represent the mean ± SD (n = 4).